Hundreds of genes interact with the yeast nuclear pore complex (NPC), localizing at the nuclear periphery and clustering with co-regulated genes.Dynamic tracking of peripheral genes shows that they cycle on and off the NPC and that interaction with the HYDRATING LOTION NPC slows their sub-diffusive movement.Furthermore, NPC-dependent inter-chromoso
A New Framework for DDoS Attack Detection and Defense in SDN Environment
While software defined network (SDN) brings more innovation to the development of future networks, it also faces a more severe threat from DDoS attacks.In order to deal Tees with the single point of failure on SDN controller caused by DDoS attacks, we propose a framework for detection and defense of DDoS attacks in the SDN environment.Firstly, we d
Physical Experimental Study on the Wave Reflection and Run-Up of a New Ecological Hollow Cube
Implementing quadrangular hollow blocks on breakwaters is a common method for wave mitigation and ocean disaster prevention.In order to improve the wave-damping performance of conventional quadrangular hollow blocks, a new quadrangular hollow block is proposed.In this study, a series of physical modeling experiments were conducted in a two-dimensio
Identification of the role of SNARE proteins in rAAV vector production through interaction with the viral MAAP
Adeno-associated virus (AAV) expresses a membrane-associated accessory protein (MAAP), a small nonstructural protein, that facilitates AAV secretion out of the plasma membrane through an association with extracellular vesicles during AAV egress.Here, we investigated the host proteins that interact with AAV2 MAAP (MAAP2) using APEX2-mediated proximi